WeightLossComparison WeightLossComparison
Weight Loss Comparison

Compare UK weight-loss tablets and capsules

UK weight-loss tablet and capsule treatments cover significantly different medicines, mechanisms and access pathways. Orlistat works in the gut. Mysimba acts centrally on appetite and reward pathways. Rybelsus is oral semaglutide — but is licensed for type 2 diabetes, not weight management. Future oral GLP-1 options for weight management are in development but not yet licensed in the UK. Understanding each route before comparing providers helps you interpret what you are actually looking at.

Person discussing tablet medication at a table with a pen and blister pack
Tablet and capsule comparison

Compare current UK tablet and capsule treatments, including Orlistat, Xenical and Mysimba. See how providers show pack sizes, prices, assessments, delivery and support before you narrow down your options.

  • Generic orlistat: Orlistat
  • Branded orlistat: Xenical
  • Different oral route: Mysimba
How tablets compare

Tablet prices need pack and assessment detail

A low listed price is only useful when you know what it covers. Check whether the route is generic or branded, what pack size is shown, how the provider assesses suitability and what happens after the first supply.

  • Generic or branded
  • Pack size
  • Assessment checks
  • Delivery and support
Illustration of tablet packs, capsules and provider comparison cards.
Treatment routes

Current tablet and capsule treatments

Use these cards for a quick route overview, then open the individual treatment pages when you want more detail on a specific tablet or capsule option.

Capsule

Orlistat

Generic orlistat is usually listed by capsule pack size, so the pack description matters as much as the headline price.

  • Active ingredient: orlistat
  • Provider coverage: 15 providers, 28 price rows
  • Lowest listed price: From £17.39
  • Pack details found: 84 capsules / 28 days, 84 capsules, 84 capsules /...
View treatment page
Capsule

Xenical

Xenical is branded orlistat. It is useful to compare it with generic orlistat by pack size, provider checks and price.

  • Active ingredient: orlistat
  • Provider coverage: 12 providers, 21 price rows
  • Lowest listed price: From £29.98
  • Pack details found: 84 capsules / 28 days, 84 capsules, Starting price shown,...
View treatment page
Tablet

Mysimba

Mysimba uses different active ingredients from orlistat, so suitability checks and provider support matter as much as price.

  • Active ingredients: naltrexone/bupropion
  • Provider coverage: 10 providers, 18 price rows
  • Lowest listed price: From £97.00
  • Pack details found: 112 tablets / first month, 112 tablets, Starting price shown,...
View treatment page
Additional oral route

Alli

Alli appears in the wider oral-treatment market. Check strength and pack size before comparing it with prescription routes.

  • Active ingredient: orlistat
  • Provider coverage: 10 providers
  • Lowest listed price: From £39.50
Additional oral route

Orlos

Orlos appears in some provider data as another orlistat-based route. Check pack details before comparing prices.

  • Active ingredient: orlistat
  • Provider coverage: 8 providers
  • Lowest listed price: From £14.99
How providers usually assess

How providers usually assess tablet requests

Many providers describe an online assessment before treatment is considered. The questions, pack details and follow-up support can make two similar-looking prices feel quite different.

1

Suitability questions

Providers may ask about BMI, medical history, medicines, previous treatment and whether the oral route is suitable.

2

Pack and price basis

Check whether the price is for a starter pack, monthly supply, 28-day supply or another pack description.

3

Follow-up and support

Look for repeat checks, delivery terms, support access and what happens if treatment is paused or changed.

Questions to check

Before you compare provider prices

Is it the same medicine route?

Orlistat and Xenical are closely related, while Mysimba uses different active ingredients. Compare like with like before focusing on price.

Is the pack size the same?

Provider prices may refer to different pack sizes, monthly supply descriptions or starting-price rows. Check the pack description before comparing totals.

What support is included?

Look for assessment information, repeat checks, delivery terms and clear information about follow-up or support.

Oral GLP-1 context

Oral GLP-1 tablets are a separate “watch” topic

Oral GLP-1 weight-loss tablets are now approved in the US, but no GLP-1 tablet is currently approved in the UK for weight loss. This page focuses on current UK tablet and capsule options, with a separate guide for oral GLP-1 developments.

  • Current UK tablet treatments
  • Emerging oral GLP-1 context
  • Availability can differ by country
Read oral GLP-1 tablet guide
Next steps

Continue comparing oral treatment routes

All treatments

Use the all-treatments hub when you want one place to compare injection and oral routes.

Providers

Browse provider pages once you know which route you want to compare next.

Before you decide

Confirm the latest details before you continue

Tablet prices, pack sizes, delivery terms and eligibility details can change. Start with the comparison, then confirm the current details directly with the provider.

Tablet comparison

Compare tablet and capsule prices by provider

Filter by oral route, then compare pack details, listed price, estimated 28-day cost, delivery and checks.

OrlistatXenicalMysimbaAlliOrlos
Swipecards
ProviderTreatment routePack / supply shownListed price28-day estimateDeliveryAssessment / checksChecked
Click PharmacyProvider pageAlli84 capsules
listed price£34.99
£34.99£0.00Online Consultation And Prescriber Review15 Jun 2026View
Superdrug Online DoctorProvider pageAlli84 capsules
listed price£39.50
£39.50£0.00Online Questionnaire And Doctor Review3 Jun 2026View
Superdrug Online DoctorProvider pageAlli84 capsules / 28 days
listed price£39.50
£39.50Not shownClinician Approval25 Apr 2026View
Oxford Online PharmacyProvider pageAlli84 capsules
listed price£39.98
£39.98Not shownOnline Consultation16 Jun 2026View
AsdaProvider pageAlli84 capsules
listed price£39.99
£39.99£0.00Online Questionnaire And Doctor Review3 Jun 2026View
Asda Online DoctorProvider pageAlli84 capsules / 28 days
listed price£39.99
£39.99Not shownQuestionnaire And Review25 Apr 2026View
Doctor-4-UProvider pageAlli84 capsules
listed price£44.99
£44.99£1.99Retail Product Page3 Jun 2026View
PharmicaProvider pageAlli84 capsules
listed price£44.99
£44.99Not shownOnline Consultation3 Jun 2026View
Click 2 PharmacyProvider pageAlli84 capsules / 28 days
listed price£49.99
£49.99Not shownPharmacist Review3 Jun 2026View
The Independent PharmacyProvider pageAlli84 capsules
listed price£49.99
£49.99£2.99Online Assessment3 Jun 2026View
UK MedsProvider pageAlliStarting price shown
listed price£55.99
£55.99£0.00Pharmacist Review17 Jun 2026View
Pharmacy2UProvider pageAlli84 capsules
listed price£98.28
£98.28Not shownPharmacy Medicine Questions3 Jun 2026View
ZavaProvider pageAlli84 capsules
listed price£99.00
£99.00£0.00Otc Route With Suitability Checks3 Jun 2026View
Medical SpecialistsProvider pageMysimba112 tablets / first pack
listed price£97.00
£97.00Not shownOnline Consultation3 Jun 2026View
Health ExpressProvider pageMysimbaFrom £97.99 / 1 month
listed price£97.99
£97.99£0.00Online Consultation And Doctor Approval3 Jun 2026View
AsdaProvider pageMysimba112 tablets
listed price£99.00
£99.00£0.00Online Questionnaire And Doctor Review3 Jun 2026View
Asda Online DoctorProvider pageMysimba112 tablets / first month
listed price£99.00
£99.00Not shownDoctor Review25 Apr 2026View
ZavaProvider pageMysimba112 tablets
listed price£99.00
£99.00£0.00Online Consultation And Doctor Review3 Jun 2026View
Chemist4UProvider pageMysimbaStarting price shown
listed price£99.99
£99.99£3.95Consultation And Private Prescription Included3 Jun 2026View
Cloud PharmacyProvider pageMysimba112 tablets
listed price£109.00
£109.00£0.00Free Online Consultation3 Jun 2026View
Oxford Online PharmacyProvider pageMysimbaStarter pack / product page price
listed price£109.98
£109.98Not shownOnline Consultation16 Jun 2026View
Click 2 PharmacyProvider pageMysimba112 tablets / first pack
listed price£109.99
£109.99Not shownFree Online Consultation3 Jun 2026View
Click PharmacyProvider pageMysimba1 month (112 tablets)
listed price£109.99
£109.99£0.00Online Consultation And Prescriber Review15 Jun 2026View
Click 2 PharmacyProvider pageMysimba1 box / 112 tablets
listed price£109.99
£109.99Not shownFree Online Consultation25 Apr 2026View
Superdrug Online DoctorProvider pageMysimba112 tablets
listed price£115.00
£115.00£0.00Online Questionnaire And Doctor Review3 Jun 2026View
Superdrug Online DoctorProvider pageMysimba112 tablets / month
listed price£115.00
£115.00Not shownClinician Approval25 Apr 2026View
Treated UKProvider pageMysimba112 tablets / first pack
listed price£143.95
£143.95Not shownOnline Consultation And Clinical Review3 Jun 2026View
Cloud PharmacyProvider pageOrlistat42 capsules
listed price£17.39
£33.98£0.00Free Online Consultation3 Jun 2026View
PharmicaProvider pageOrlistat84 capsules
listed price£21.99
£21.99Not shownOnline Consultation3 Jun 2026View
UK MedsProvider pageOrlistatStarting price shown
listed price£27.99
£27.99£0.00Doctor Review3 Jun 2026View
The Independent PharmacyProvider pageOrlistat84 capsules
listed price£29.89
£29.89£2.99Online Assessment3 Jun 2026View
Oxford Online PharmacyProvider pageOrlistat84 capsules / 28 days
listed price£29.99
£29.99Not shownOnline Consultation16 Jun 2026View
Click PharmacyProvider pageOrlistat42 tablets
listed price£32.99
£32.99£0.00Online Consultation And Prescriber Review15 Jun 2026View
Chemist4UProvider pageOrlistat84 pack / 28 days
listed price£33.59
£33.59£3.95Consultation And Private Prescription Included3 Jun 2026View
Click 2 PharmacyProvider pageOrlistat84 capsules / 28 days
listed price£33.60
£33.60Not shownFree Online Consultation3 Jun 2026View
Doctor-4-UProvider pageOrlistat84 capsules
listed price£36.99
£36.99£1.99Online Doctor Questionnaire3 Jun 2026View
Bolt PharmacyProvider pageOrlistat84 capsules / 4 weeks
listed price£38.99
£38.99Not shownOnline Assessment21 May 2026View
MedExpressProvider pageOrlistat84 capsules / 4 weeks
listed price£38.99
£38.99£0.00Online Consultation3 Jun 2026View
Well PharmacyProvider pageOrlistat84 capsules / 28 days
listed price£42.99
£42.99Not shownRetail Product Page3 Jun 2026View
AsdaProvider pageOrlistat84 capsules
listed price£44.00
£44.00£0.00Online Questionnaire And Doctor Review3 Jun 2026View
Asda Online DoctorProvider pageOrlistat84 capsules / 28 days
listed price£44.00
£44.00Not shownDoctor Review25 Apr 2026View
Superdrug Online DoctorProvider pageOrlistat84 capsules
listed price£49.99
£49.99£0.00Online Questionnaire And Doctor Review3 Jun 2026View
Superdrug Online DoctorProvider pageOrlistat84-capsule equivalent
listed price£49.99
£49.99Not shownClinician Approval25 Apr 2026View
ZavaProvider pageOrlistat42 capsules starting pack
listed price£74.99
£95.00£0.00Online Consultation And Doctor Review3 Jun 2026View
PharmicaProvider pageOrlos84 capsules
listed price£14.99
£14.99Not shownOnline Consultation3 Jun 2026View
Oxford Online PharmacyProvider pageOrlos84 capsules
listed price£18.98
£18.98Not shownOnline Consultation16 Jun 2026View
MedExpressProvider pageOrlos84 capsules / 4 weeks
listed price£18.99
£18.99£0.00Online Consultation3 Jun 2026View
Lloyds PharmacyProvider pageOrlos84 capsules / 28 days
listed price£22.89
£22.89Not shownRetail Product Page22 May 2026View
The Independent PharmacyProvider pageOrlos84 capsules
listed price£24.99
£24.99£2.99Online Assessment3 Jun 2026View
Doctor-4-UProvider pageOrlos84 capsules
listed price£26.99
£26.99£1.99Retail Product Page3 Jun 2026View
AsdaProvider pageOrlos84 capsules
listed price£35.98
£35.98£0.00Online Questionnaire And Doctor Review3 Jun 2026View
Pharmacy2UProvider pageOrlos84 capsules
listed price£67.30
£67.30Not shownPharmacy Medicine Questions3 Jun 2026View
ZavaProvider pageOrlos84 capsules
listed price£99.00
£99.00£0.00Otc Route With Suitability Checks3 Jun 2026View
Cloud PharmacyProvider pageXenical42 capsules
listed price£29.98
£44.50£0.00Free Online Consultation3 Jun 2026View
Click PharmacyProvider pageXenical42 tablets
listed price£34.99
£34.99£0.00Online Consultation And Prescriber Review15 Jun 2026View
MedExpressProvider pageXenical84 capsules / 4 weeks
listed price£38.99
£38.99£0.00Online Consultation3 Jun 2026View
Oxford Online PharmacyProvider pageXenical84 capsules / 28 days
listed price£44.19
£44.19Not shownOnline Consultation16 Jun 2026View
Click 2 PharmacyProvider pageXenical84 capsules / 28 days
listed price£44.49
£44.49Not shownFree Online Consultation3 Jun 2026View
PharmicaProvider pageXenicalPrice checker starting price
listed price£51.99
£51.99Not shownOnline Consultation3 Jun 2026View
AsdaProvider pageXenical84 capsules
listed price£52.00
£52.00£0.00Online Questionnaire And Doctor Review3 Jun 2026View
Asda Online DoctorProvider pageXenical84 capsules / 28 days
listed price£52.00
£52.00Not shownDoctor Review25 Apr 2026View
Superdrug Online DoctorProvider pageXenical84 capsules
listed price£57.99
£57.99£0.00Online Questionnaire And Doctor Review3 Jun 2026View
Superdrug Online DoctorProvider pageXenical84 capsules / 28 days
listed price£57.99
£57.99Not shownClinician Approval25 Apr 2026View
Doctor-4-UProvider pageXenical42 capsules
listed price£59.99
£59.99£1.99Online Doctor Questionnaire3 Jun 2026View
The Independent PharmacyProvider pageXenical84 capsules
listed price£59.99
£59.99£2.99Online Assessment3 Jun 2026View
UK MedsProvider pageXenicalStarting price shown
listed price£65.99
£65.99£0.00Doctor Review3 Jun 2026View
ZavaProvider pageXenical84 capsules
listed price£89.95
£89.95£0.00Online Consultation And Doctor Review3 Jun 2026View
Pharmacy OnlineProvider pageXenicalStarting price shown
listed price£90.99
£90.99Not shownOnline Consultation And Clinical Review22 May 2026View
ZavaProvider pageOrlistat
42 capsules starting pack£74.99
28-day
£95.00
Delivery
£0.00
Checks
Online Consultation And Doctor Review
Checked
3 Jun 2026
View provider