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Comparison guide

Orlistat vs Mysimba

Compare Orlistat and Mysimba in plain English so you can see why they are not the same kind of tablet option before you look at providers.

Last reviewed: 2026-04-25Reviewer: Editorial team
Quick comparison

The main differences to check first

Main difference

Orlistat-family options often depend on brand, strength and pack details. Mysimba raises different prescription assessment and monitoring questions.

Useful for comparing

Medicine name, access type, pack size, safety restrictions and when the details were checked.

Where to compare providers

Use this site’s tablet cards only where the provider page clearly shows medicine, pack, route and price evidence.

Tablet comparison

Tablet options with enough detail to compare

Use these medicine cards to see which tablet details are clear enough to compare before you move into the provider cards below.

15
providers
20
checks
2
medicines covered
Date pending
last source check
Orlistat 120mg

Orlistat 120mg provider options

Compare generic Orlistat providers by pack size, access type and last-checked price information.

Providers
14
Price guide
£23.98
Access
Prescription Only
Reviewed
Date pending
Mysimba 8mg/90mg

Mysimba 8mg/90mg provider options

Compare Mysimba providers carefully because assessment, monitoring and pack details matter as much as price.

Providers
6
Price guide
£99.00
Access
Prescription Only
Reviewed
Date pending
Quick answer

Orlistat and Mysimba are very different tablet options

Short version: Orlistat is usually compared by strength, pack size, brand/generic name and access route. Mysimba is a different prescription medicine combination, so assessment, contraindications, interactions and follow-up become more central.

Best next step: use Orlistat pages when your question is about orlistat-family packs and brands. Use Mysimba pages when your question is about a different prescription tablet route.

01

Best for pack comparison

Orlistat-family options, where strength, capsule count and access route matter.

02

Best for assessment comparison

Mysimba, where clinical suitability and monitoring questions are more central.

03

Not a like-for-like price check

A lower fee is not meaningful if the medicine and comparison basis are different.

Side-by-side comparison

Orlistat vs Mysimba: main differences

Question Orlistat Mysimba Decision point
Medicine type Orlistat-family medicine. Naltrexone/bupropion combination. Different active ingredients mean different suitability checks.
Best for comparing Pack size, strength, generic/brand route and access type. Assessment, contraindications, interactions and follow-up. Choose the comparison based on the treatment question, not just price.
Provider table focus Capsule count, 28-day guide, stock and pharmacy/prescriber route. Prescription assessment, month/titration context and monitoring. Provider cards should show enough detail to compare fairly.
Cost comparison Useful when pack and strength are clear. Useful only when pack/month basis and assessment route are clear. Do not compare unclear packs as if they are equal.
Best for

Which page should you use?

Generic Orlistat

Best when you want pack, strength and generic medicine comparison.

Xenical

Best when you want the branded orlistat comparison.

Alli or Orlos

Best when comparing lower-dose pharmacy-led orlistat-family options.

Mysimba

Best when comparing a different prescription tablet route with stronger assessment questions.

Orlistat: pros and cons to compare

  • Pack and strength can often be compared clearly.
  • Brand, generic and lower-dose routes can be confused.
  • Pharmacy or prescriber checks still matter.

Mysimba: pros and cons to compare

  • Distinct prescription tablet route.
  • Assessment, warnings and interactions are central.
  • Not a simple substitute for orlistat-family options.
Provider options

Compare current Orlistat and Mysimba provider options

The cards below appear where medicine, pack or access information is clear enough to compare. Confirm current details directly with the provider.

Tablet and capsule comparison

Compare tablet options without a wall of figures

Use these cards to see the medicine, provider, access type, price basis, stock information and last-checked date in a simpler format. They are here to help you decide what to verify next.

20
tablet options shown
2
tablet options covered
No
paid ranking
Tablet prices use a normalised 28-day basis where the pack data allows it. Prices, stock, delivery, consultation requirements and eligibility can change, so confirm current details with the provider.
Ashcroft Pharmacy logo
Orlistat 120mg

Ashcroft Pharmacy

Pharmacy Led · Prescription Only

Pack/price basis
120mg capsules; 84 capsules; 28-day equivalent
28-day guide
Around £23.98 for 28 days
Assessment
Assessment required: online assessment; Delivery from £2.49
Status
Unclear; reviewed 26 Apr 2026
The Independent Pharmacy logo
Orlistat 120mg

The Independent Pharmacy

Pharmacy Led · Prescription Only

Pack/price basis
One 84-capsule pack; price shown before consultation
28-day guide
Around £29.89 for 28 days
Assessment
Assessment required: online consultation; Delivery not confirmed
Status
In Stock; reviewed 27 Apr 2026
Orlistat 120mg

Oxford Online Pharmacy

Online Doctor · Prescription Only

Pack/price basis
84 capsules; 28-day equivalent
28-day guide
Around £29.99 for 28 days
Assessment
Assessment required: online consultation and clinical review; consultation included; Delivery not confirmed
Status
Unclear; reviewed 1 May 2026
Orlistat 120mg

Chemist4U

Online Doctor · Prescription Only

Pack/price basis
84 pack; 28-day equivalent
28-day guide
Around £33.59 for 28 days
Assessment
Assessment required: consultation and private prescription included; consultation included; Delivery not confirmed
Status
Unclear; reviewed 1 May 2026
Click2Pharmacy logo
Orlistat 120mg

Click2Pharmacy

Pharmacy Led · Prescription Only

Pack/price basis
84 capsules; 28-day equivalent
28-day guide
Around £33.60 for 28 days
Assessment
Assessment required: free online consultation; Delivery not confirmed
Status
In Stock; reviewed 25 Apr 2026
Orlistat 120mg

Doctor-4-U

Online Doctor · Prescription Only

Pack/price basis
84 capsules; 28-day equivalent
28-day guide
Around £36.99 for 28 days
Assessment
Assessment required: doctor consultation included; consultation included; Delivery from £1.99
Status
Unclear; reviewed 1 May 2026
MedExpress logo
Orlistat 120mg

MedExpress

Online Doctor · Prescription Only

Pack/price basis
84 capsules; delivery from GBP 2.90
28-day guide
Around £38.99 for 28 days
Assessment
Assessment required: online consultation; Delivery from £2.90
Status
Unclear; reviewed 25 Apr 2026
Asda Online Doctor logo
Orlistat 120mg

Asda Online Doctor

Online Doctor · Prescription Only

Pack/price basis
84 capsules; 28-day equivalent
28-day guide
Around £44.00 for 28 days
Assessment
Assessment required: doctor review; consultation included; Delivery not confirmed
Status
In Stock; reviewed 25 Apr 2026
QuickMeds logo
Orlistat 120mg

QuickMeds

Pharmacy Led · Prescription Only

Pack/price basis
28-day supply; displayed pre-consultation
28-day guide
Around £45.99 for 28 days
Assessment
Assessment required: online consultation; Delivery not confirmed
Status
In Stock; reviewed 26 Apr 2026
Well Pharmacy logo
Orlistat 120mg

Well Pharmacy

Pharmacy Led · Prescription Only

Pack/price basis
84 capsules; 28-day equivalent
28-day guide
Around £45.99 for 28 days
Assessment
Assessment required: pharmacist-led service; Delivery not confirmed
Status
Unclear; reviewed 25 Apr 2026
Superdrug Online Doctor logo
Orlistat 120mg

Superdrug Online Doctor

Online Doctor · Prescription Only

Pack/price basis
84 capsules; 28-day equivalent
28-day guide
Around £49.99 for 28 days
Assessment
Assessment required: clinician approval; consultation included; Delivery not confirmed
Status
In Stock; reviewed 25 Apr 2026
Cloud Pharmacy logo
Orlistat 120mg

Cloud Pharmacy

Pharmacy Led · Prescription Only

Pack/price basis
Starting price; normalisation pending pack detail
28-day guide
28-day guide pending
Assessment
Assessment required: free consultation; Delivery not confirmed
Status
Unclear; reviewed 25 Apr 2026
Pharmica logo
Orlistat 120mg

Pharmica

Pharmacy Led · Prescription Only

Pack/price basis
Starting price; normalisation pending pack detail
28-day guide
28-day guide pending
Assessment
Assessment required: online consultation; Delivery not confirmed
Status
Unclear; reviewed 25 Apr 2026
ZAVA UK logo
Orlistat 120mg

ZAVA UK

Online Doctor · Prescription Only

Pack/price basis
Displayed bundle; 28-day equivalent pending pack detail
28-day guide
28-day guide pending
Assessment
Assessment required: doctor decision after consultation; consultation included; Delivery included/free
Status
In Stock; reviewed 25 Apr 2026
Asda Online Doctor logo
Mysimba 8mg/90mg

Asda Online Doctor

Online Doctor · Prescription Only

Pack/price basis
112 tablets; titration-aware month
28-day guide
Around £99.00 for 28 days
Assessment
Assessment required: doctor review; consultation included; Delivery not confirmed
Status
In Stock; reviewed 25 Apr 2026
Click2Pharmacy logo
Mysimba 8mg/90mg

Click2Pharmacy

Pharmacy Led · Prescription Only

Pack/price basis
112 tablets; titration-aware month
28-day guide
Around £109.99 for 28 days
Assessment
Assessment required: free online consultation; Delivery not confirmed
Status
In Stock; reviewed 25 Apr 2026
Medicine Marketplace logo
Mysimba 8mg/90mg

Medicine Marketplace

Pharmacy Led · Prescription Only

Pack/price basis
112 tablets; titration-aware month; observed band varies
28-day guide
Around £115.00 for 28 days
Assessment
Assessment required: online assessment; Delivery not confirmed
Status
Unclear; reviewed 25 Apr 2026
Superdrug Online Doctor logo
Mysimba 8mg/90mg

Superdrug Online Doctor

Online Doctor · Prescription Only

Pack/price basis
112 tablets; titration-aware month
28-day guide
Around £115.00 for 28 days
Assessment
Assessment required: clinician approval; consultation included; Delivery not confirmed
Status
In Stock; reviewed 25 Apr 2026
Cloud Pharmacy logo
Mysimba 8mg/90mg

Cloud Pharmacy

Pharmacy Led · Prescription Only

Pack/price basis
Starting price; normalisation pending pack detail
28-day guide
28-day guide pending
Assessment
Assessment required: free consultation; Delivery not confirmed
Status
Unclear; reviewed 25 Apr 2026
ZAVA UK logo
Mysimba 8mg/90mg

ZAVA UK

Online Doctor · Prescription Only

Pack/price basis
Displayed bundle; 28-day equivalent pending pack detail
28-day guide
28-day guide pending
Assessment
Assessment required: doctor decision after consultation; consultation included; Delivery included/free
Status
In Stock; reviewed 25 Apr 2026
Provider Tablet option Access type Pack/price basis 28-day guide Assessment Status Read next
Ashcroft Pharmacy logo Ashcroft Pharmacy Pharmacy Led Orlistat 120mg
120mg
Prescription Only 120mg capsules; 84 capsules; 28-day equivalent Around £23.98 for 28 days Assessment required: online assessment; Delivery from £2.49 Unclear; reviewed 26 Apr 2026 View provider
The Independent Pharmacy logo The Independent Pharmacy Pharmacy Led Orlistat 120mg
120mg
Prescription Only One 84-capsule pack; price shown before consultation Around £29.89 for 28 days Assessment required: online consultation; Delivery not confirmed In Stock; reviewed 27 Apr 2026 View provider
Oxford Online Pharmacy Online Doctor Orlistat 120mg
120mg
Prescription Only 84 capsules; 28-day equivalent Around £29.99 for 28 days Assessment required: online consultation and clinical review; consultation included; Delivery not confirmed Unclear; reviewed 1 May 2026 View provider
Chemist4U Online Doctor Orlistat 120mg
120mg
Prescription Only 84 pack; 28-day equivalent Around £33.59 for 28 days Assessment required: consultation and private prescription included; consultation included; Delivery not confirmed Unclear; reviewed 1 May 2026 View provider
Click2Pharmacy logo Click2Pharmacy Pharmacy Led Orlistat 120mg
120mg
Prescription Only 84 capsules; 28-day equivalent Around £33.60 for 28 days Assessment required: free online consultation; Delivery not confirmed In Stock; reviewed 25 Apr 2026 View provider
Doctor-4-U Online Doctor Orlistat 120mg
120mg
Prescription Only 84 capsules; 28-day equivalent Around £36.99 for 28 days Assessment required: doctor consultation included; consultation included; Delivery from £1.99 Unclear; reviewed 1 May 2026 View provider
MedExpress logo MedExpress Online Doctor Orlistat 120mg
120mg
Prescription Only 84 capsules; delivery from GBP 2.90 Around £38.99 for 28 days Assessment required: online consultation; Delivery from £2.90 Unclear; reviewed 25 Apr 2026 View provider
Asda Online Doctor logo Asda Online Doctor Online Doctor Orlistat 120mg
120mg
Prescription Only 84 capsules; 28-day equivalent Around £44.00 for 28 days Assessment required: doctor review; consultation included; Delivery not confirmed In Stock; reviewed 25 Apr 2026 View provider
QuickMeds logo QuickMeds Pharmacy Led Orlistat 120mg
120mg
Prescription Only 28-day supply; displayed pre-consultation Around £45.99 for 28 days Assessment required: online consultation; Delivery not confirmed In Stock; reviewed 26 Apr 2026 View provider
Well Pharmacy logo Well Pharmacy Pharmacy Led Orlistat 120mg
120mg
Prescription Only 84 capsules; 28-day equivalent Around £45.99 for 28 days Assessment required: pharmacist-led service; Delivery not confirmed Unclear; reviewed 25 Apr 2026 View provider
Superdrug Online Doctor logo Superdrug Online Doctor Online Doctor Orlistat 120mg
120mg
Prescription Only 84 capsules; 28-day equivalent Around £49.99 for 28 days Assessment required: clinician approval; consultation included; Delivery not confirmed In Stock; reviewed 25 Apr 2026 View provider
Cloud Pharmacy logo Cloud Pharmacy Pharmacy Led Orlistat 120mg
120mg
Prescription Only Starting price; normalisation pending pack detail 28-day guide pending Assessment required: free consultation; Delivery not confirmed Unclear; reviewed 25 Apr 2026 View provider
Pharmica logo Pharmica Pharmacy Led Orlistat 120mg
120mg
Prescription Only Starting price; normalisation pending pack detail 28-day guide pending Assessment required: online consultation; Delivery not confirmed Unclear; reviewed 25 Apr 2026 View provider
ZAVA UK logo ZAVA UK Online Doctor Orlistat 120mg
120mg
Prescription Only Displayed bundle; 28-day equivalent pending pack detail 28-day guide pending Assessment required: doctor decision after consultation; consultation included; Delivery included/free In Stock; reviewed 25 Apr 2026 View provider
Asda Online Doctor logo Asda Online Doctor Online Doctor Mysimba 8mg/90mg
8mg/90mg
Prescription Only 112 tablets; titration-aware month Around £99.00 for 28 days Assessment required: doctor review; consultation included; Delivery not confirmed In Stock; reviewed 25 Apr 2026 View provider
Click2Pharmacy logo Click2Pharmacy Pharmacy Led Mysimba 8mg/90mg
8mg/90mg
Prescription Only 112 tablets; titration-aware month Around £109.99 for 28 days Assessment required: free online consultation; Delivery not confirmed In Stock; reviewed 25 Apr 2026 View provider
Medicine Marketplace logo Medicine Marketplace Pharmacy Led Mysimba 8mg/90mg
8mg/90mg
Prescription Only 112 tablets; titration-aware month; observed band varies Around £115.00 for 28 days Assessment required: online assessment; Delivery not confirmed Unclear; reviewed 25 Apr 2026 View provider
Superdrug Online Doctor logo Superdrug Online Doctor Online Doctor Mysimba 8mg/90mg
8mg/90mg
Prescription Only 112 tablets; titration-aware month Around £115.00 for 28 days Assessment required: clinician approval; consultation included; Delivery not confirmed In Stock; reviewed 25 Apr 2026 View provider
Cloud Pharmacy logo Cloud Pharmacy Pharmacy Led Mysimba 8mg/90mg
8mg/90mg
Prescription Only Starting price; normalisation pending pack detail 28-day guide pending Assessment required: free consultation; Delivery not confirmed Unclear; reviewed 25 Apr 2026 View provider
ZAVA UK logo ZAVA UK Online Doctor Mysimba 8mg/90mg
8mg/90mg
Prescription Only Displayed bundle; 28-day equivalent pending pack detail 28-day guide pending Assessment required: doctor decision after consultation; consultation included; Delivery included/free In Stock; reviewed 25 Apr 2026 View provider

Common questions

Are Orlistat and Mysimba interchangeable?

No. They are different medicine routes and need different suitability checks.

Which is better?

There is no universal answer. Orlistat is better for pack/brand comparison. Mysimba is better treated as a separate prescription-tablet decision requiring assessment.

Can I compare by price alone?

No. Compare medicine, pack, access route, assessment and review date before relying on price.


Before you decide: Prices, availability, eligibility and offer details can change. Use this page as a comparison guide, then confirm current information directly with the provider.

Source notes

These notes explain the basis for the page in plain English: what was checked, when it was checked and where the information came from.

Mysimba Prescribing Information

The Mysimba Summary of Product Characteristics was reviewed for medicine identity and prescribing-information context.

Checked27 April 2026ConfidenceHigh

Source: eMC: Mysimba 8 mg/90 mg prolonged-release tablets SmPC

Reviewed to explain why Mysimba should be compared more cautiously than a simple tablet-price comparison suggests.

View source

Xenical Prescribing Information

The Xenical Summary of Product Characteristics was reviewed for medicine identity and branded-orlistat context.

Checked27 April 2026ConfidenceHigh

Source: eMC: Xenical 120 mg hard capsules SmPC

Reviewed to explain why Xenical sits inside the orlistat family and still needs pack and route checking.

View source

Alli Prescribing Information

The alli Summary of Product Characteristics was reviewed for medicine identity and lower-dose orlistat-family context.

Checked27 April 2026ConfidenceHigh

Source: eMC: alli 60 mg hard capsules SmPC

Reviewed to explain why Alli sits inside the orlistat family rather than as a separate active ingredient.

View source

Nhs Orlistat Context

NHS medicines information was reviewed for orlistat background.

Checked27 April 2026ConfidenceHigh

Source: NHS medicines: Orlistat

Reviewed for broad public explanation of the orlistat route and why pack and access details matter.

View source

Important information

This website is an informational comparison hub. It does not prescribe, supply or sell prescription-only medicines. Suitability depends on a regulated clinical assessment.

Some links may be affiliate or commercial links. Commercial relationships must not change the way safety, eligibility, checked details or editorial context are presented.